The fuse is blowing before the balls start kicking out of the trough. Once the fuse blows, power to the optos is killed and the game thinks the trough is fully loaded so it starts kicking out balls.
The light up topper is likely a problem. The extra current pulled by the LEDs could be enough to blow the fuse when all 12V motors are active.
Make sure you are using a slow blow fuse at F116.
Try unplugging the topper and see if it's still blowing. If that fixes it you'll need to either increase the fuse by the smallest amount to accommodate the topper or wire in an external 12V supply for the topper.
The generally accepted solution is to use an external supply to avoid excess heating of the board's unregulated 12V supply.