Start isolating things that use 12v/5v. Unplug the sound board.
Unplug the displays and try again. Do you have replacement displays? If so you are probably overloading the 5v/12v circuit and popping the fuse. Replacement LED displays use the 5v line instead of the +185v. I am not familiar with the replacement driver board to tell you if it is safe to up the fuse. That might be a question for for the manufacturer of the display/driver board.
Great to see you're enjoying Pinside! Did you know Pinside is able to run thanks to donations from our visitors? Please donate to Pinside, support the site and get anext to your username to show for it! Donate to Pinside