Is the autograph >$100 or did that include admission to ComicCon?
It is customary to "tip" (or purchase a book or whatever) for an autograph but $120 seems excessive. If that includes admission and then a tip for the autograph ($80 to get into the event and $40 for the autograph) I would think that'd be fun and would add an interesting conversation point to your game.
I myself wouldn't pay more for an autographed game but it would show you cared about your game and hopefully took good care of it and I'd give that weight when I went to purchase.