Of course. I don't see why someone would avoid it.
Quoted from FatPanda:
I wonder if a sheet of mylar over it would work, especially if it's brand new. I could see how waxing an older game that already might have hazing or scratching would be a better choice, but I could see how mylar on a new game might keep it in better shape long term.
That's what I would do. Brand new mylar is basically invisible.
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