Before replacing Q6, may I suggest that you have more to gain by diagnosing the mute issue first.
If you hold the reset line active on power-up as I mentioned in post #48, you will see a frozen reset state of the board.
The active low /reset line coming onto the sound board at connector J1 pin 25 goes to the active low CLR input pin 10 of the 74107 (U6) which should cause the 74107 pin 6 /Q output to be high. This will switch on transistor Q6 (there will probably be around 0.8 volts on the base pin of the transistor) and cause the transistors collector pin to pull down to near zero volts which is used at the amplifier chips (pin 1) to mute their audio inputs.
Some things to note:
The output pins of U3 and U4 (used to select/enable sounds) will be in an unknown state on power-up which could cause unwanted sounds to be selected/activated (i.e. you'd hear thumps/bleeps, etc). This is the reason for having the mute circuit on reset, to block these sounds.
After the reset line is released, the very beginning of program code writes data to U3 and U4 which clears their outputs to a known state of "low" to stop any sounds being selected/enabled *and* it also triggers U6 to stop muting the amplifiers, i.e. pin 6 of U6 will go low causing the Q6 transistor to switch off and release the mute signal at the amplifiers (you mentioned somewhere that the mute signal sits around 7 volts when the mute is disabled).
The mute signal on pin 1 of the amplifiers also has a 10uF capacitor (C42) which is used to slow down the release of the mute signal.
If your logic probe/multi-meter indicates logic/voltage states other than what I've mentioned, it can help pinpoint the fault.