All of the voltages check good? Start at the power supply and go from there. Check all the connectors. That is one of the biggest issues on any Sys 1 - 80b. I can not stress that enough.
I had a gold wings that was locking up and it was the daughterboard. I reflowed the joints and it fixed it. Also my sound board led went out and it was the connector at the power supply. Turn the game on a tap on the daughterboard on the known working CPU. They are so fragile it might not be working now. Mine got messed up just from the ride home. Changing the game prom could have stressed the joints on the bottom.