Quoted from Kendvanpool:Since the ICs - U16, U18, U19 and U20 are socketed on the board I'm going to replace them to start. Any other things I should do to get started?
Do not replace a bunch of things at once. You might fix the game, but then never know the cause of the actual problem. It's not only wasted components, but possibly wasted time in the future. Additionally, after changing multiple parts at once, if you don't fix the original problem and new problems suddenly start happening, then it's a lot more confusion and time getting back to where you started.
Replace one at a time, testing the game after each one. Always be methodical.