Quoted from Rarehero:Nope. Even though the toys WERE custom for the game, they're based on the movie versions. Comic Book Green Goblin & Doc Ock especially don't look like the movie versions.
I think the Goblin toy is the only one so different from the comic book version that it would matter (the others are rather generic looking versions of the characters (Marco wore a green striped shirt in the comic books and the movie, Doc Ock had glasses, etc.). That being said I know nothing about licensing rules / laws / if there is going to be a VE, etc.