For what it's worth, I used to triple thick every glass I owned. Incidentally, at that time, every glass I owned was flaking to some capacity.
That was in 2004. While I have sold a handful of games I triple thicked then, the ones I've kept have not seen any adverse effects from using the sealant, and this includes temperature changes as well. They're all still fine, and look the same as the day I sealed them.
I've heard people run into issues when their first coat is heavy and wet. I've had great luck doing several very light, almost misty coats, until I get the desired level of sealant applied to the glass. Also, I stopped using business cards to mask off the score windows. I had a single glass where the card stuck to the paint, and pulled some up after I removed it. Since then, I spray over the glass windows and scrape the excess off. It's time consuming, but it works.