Depends on how you wish to use it. The playfield assys are the same (unless that's an era where Gottlieb printed the actual name under the score apron, but they are still plug compatible). Option settings are probably identical.
But the Relay logic related to player's and reset sequence are quite different. For 2 player games, Gottlieb used a Trip Latch (CX) 2nd Player relay for buying into a 2 player game. But for the 4 player games, they used a Coin Unit (stepper) for 1 - 4 players. The player units are similar but feature different cam arrangements and again, come into play when you are looking at the score reset circuits. So, if you are working on Ball or Player Change problems, the circuit is completely different.