Quoted from jgentry:

2nd and Broadway is often a shit show of bachelorette groups, people dressed in ways that no one wants to see, and the guy that has a family but is at a convention at the convention center so he goes crazy and does 3 lines of coke at 10 shots of jack because he hasn't been out of the house is 7 years. It's fun to see if you like the craziness but most locals never really go there anymore. It's more like a mini vegas with drunken 20 year olds everywhere and no gambling. Just don't get ran over by a peddle taven or a tractor pulling a wagon of girls that are yelling Woo for reasons that they can't even explain.
Lots of talented musicians playing all over town so just pick a bar with a cool vibe and enjoy.