Wouldn't sell enough, given today's buyers focus on familiar (to them) themes. (See home page thread from 3/27 front-paged on 3/30.)
That said, it would make a GREAT re-theme game and I'd love to see someone do it! The Justice Zone. Ace Rimmer. Miss a Cat shot and get demoted to Duane Dibbly. Shoot Lister Vindaloo Jackpots. Ball Save is a Kryten Spare Head? Video Mode with Holly (maybe multiple levels with different Hollys for each - Norman, Hattie, final level with Queeg). There's a ton of juicy material to work with.