Without seeing the specific placement. Can you put a small bolt and nut in there place? Use washers where you can.

I'd probably remove the opto, and try to fill the hole with epoxy, then re-drill it slightly smaller. Not a pro at this, but that's my first thought.

Looks like the ramp hole is actually a pass through and the threads grip the opto underneath. I would just add a small washer between the head of the screw and the ramp to even out any pressure and reduce fractures from any twisting. I could be wrong, but I don't think the screw should have real teeth into the ramp plastic.

Is the screw loose in the ramp plastic or the opto plastic?

Maybe use hot glue to fill the hole at first? If that works... great, and if not, it should be easy enough to remove and try something like a clear cast epoxy (i.e. tape one side of the hole and fill it from the other side, let cure and drill).

Edit, or another option may be to just stick (or glue) a piece of a toothpick in the opto hole to give the screw something to grip.

If it's not broke, don't fix it. Unless you're having to go back and occasionally retighten, I'd just leave it alone. MHO.

But if it is a problem, you might be able to sacrifice a $4 Horrible Freight soldering iron as a hot knife and build up the inside of the hole with a similar material. The trick is knowing what the material is to begin with. Then true up the hole with a twist drill.

If you don't plan on taking it apart again, a drop of lock tight might fix it. I would use the blue stuff as it isn't permanent.

My 2 cents... prolly double what it's worth. Best of luck.