Alcohol will remove the oils in your skin dry your hands if used a lot, skin will start to peel off.

I don't use gloves but I try not to hold the damp part of the cloth.

Some people are susceptible to adverse reactions.

I used acetone servicing printers and that was horrid skin peeling quickly stopped using that though didn't effect my work colleagues.
They soaked the rag in the stuff.
I was the first one to start using gloves.

when using alcohol I can feel the oils (skin) getting stripped away.