Depends on the people. Main of the potential buyers, at this price range, would want the game first without to care of owning a sample or not. At the same time, if you had the choice, for the same condition and few bucks more, I would buy a sample but it’s just me. I would prefer having something more unique but I’m really not part of the majority. Also if it was my second TZ i would prefer a sample too.
200 is not that rare, i would consider a real price difference (reasonable of course) for a proto.
There are around 10 to 20 proto out there... and those were assembled in slow built months before by the design team. Sample are production pins... not the same for me.