Nothing very helpful as far as mixing the game up. There is a setting for if the captured criminals stay captured on you next ball or it resets them. That is about it.
I would have really liked a "start with 1 criminal lit" "start with 2 criminals lit" ect... settings to give the game a bit more of a challenge goal wise.
There are also setting for how many center ramp hits are needed to build up to the million and other settings like that.
You can find the manual on ipdb and look through the settings than can be changed there.