If anyone dares put a Pinsound in Black Knight 2000, I hope the Black Knight personally visits and gives them a good thrashing! 
In all seriousness, a lot of the older System 11 and Data East games make use of lots of great adaptive music effects that Pinsound, to my knowledge, doesn't emulate. So if you put a Pinsound on BK2000, say goodbye to the seamless audio transitions, sounds being synced to the beat of the music, etc. Monday Night Football is another good example. That game doesn't really have much in the way of music, what makes it shine is all the short music stings and different sound/drum effects that come in and out based on what's going on in-game, all synced to the rhythm and key of the base track.
Until Pinsound is able to maintain the adaptive music functionality that lots of these games had, I'll always consider it a downgrade for any of them.