Everything everybody has said is pretty spot on. There are so many good games, in the end it really comes down to what you like as far as theme and playability.
Now I’m an old guy, so consider what I’m suggesting with that in mind. If you’d consider something other than relatively new games, that are very expensive, you could also consider something a few years old. That way you can get two! The more games you have, space permitting, the less you get burned out on any one of them.
There are a lot of very good Data East games that are popular, family friendly and quite good. Tommy, Rocky and Bullwinkle, tales from the crypt, and last action hero are pretty popular. If you buy from a reputable Pinhead, your pretty safe. In my opinion you get a lot of bang for you're buck with any of those titles. Bally and Williams games abound with great titles such as the shadow, Dracula and a bunch of others. My experience is they’re also all very reliable. A lot of people love twilight zone. I had one for almost 20 years, but it’s a really deep game with a lot going on, and maybe too difficult to be fun. Adam’s family is very popular.
If you are looking for a modern game that’s a re-issue, Monster Bash is definitely a top-tier game that’s really fun to play, and can be really easy to play too. I have Mars Attacks, and while I like it, and I know I’m in the minority here, I think it gets kind of repetitious. For me it’s a good game if you have five or more games.
Right now, I’m kind of going through a Data East phase. If nothing else, I’d suggest looking at some of those titles. They are fun for the family. Some of them have quite a depth of modes and can be both fun to bat around, or get serious with. I have a Tommy that I just love. You can’t beat the Tommy blinders for an outstanding physical mode. You can get them at reasonable prices, and I have found them to be very reliable.