Oh my! This "idea" is morphing into a catastrophe! It would appear that there are enough MPU's to go around and that only the main chip(s) is/are Unobtainium (Unless you are CoreyStup LOL). If the rest of the board is populated with 6520's (which are simply 6821 PIAs) as the interfacing to the outside world, then the most sensible approach, IMO, is to simply make a piggy back MPU to go in place of one or two of the main chips to access the Address and Data buses. Thereby reusing the rest of the board as is.
While it could be done with a $2 Microcontroller and some support hardware, others out there would probably want to use a Raspberry Pi or some similar variant with enough processing power to launch the cocktail to the moon!
Sadly, not every game deserves saving. And most of these games rank barely above the Bally Home games as far as value or collectibility go.