Because of a prior career, I have been to more metro areas of this country in about a 5 year period than most will in their entire lives.
Call me crazy, but I have never found trouble anywhere, unless:
1: I was foolishly in an area, at a time, I shouldn't have been (draw your own conclusions, but think alley ways late at night in unfamiliar areas, areas where non-locals shouldn't be to begin with, etc.)
or
2: I was looking for it.
I would imagine most folks in general would echo the above sentiments about practically anywhere in the USA.
Maybe Airbnb a place for two weeks and see if you like it before you pack your bindle and move there?