Quoted from jawjaw:

I have both led and gi ocd boards in all four of my older games. Makes a huge difference to me. Games look more fluid and natural with all the benefits of leds. You also can tune the brightness. I did that on my FH I just finished up. Inserts were way too bright for my liking so I turned them all down. Some larger inserts needed a little more brightness so I adjusted those. In the end, I got everything exactly like I wanted with all the fade effects and no ghosting.
I don't think you can run non ghosting bulbs with these boards, though. They will prevent fading effects since they are designed to only turn on at full power.

Quoted from herg:

There are varying opinions on this, but I think you can get acceptable results with non-ghosting LEDs plus LED OCD. It helps to use the software to increase the minimum brightness level to around 40% in order to avoid the "non-ghosting uncertainty area". It's just harder to get consistent results since there is extra hardware between the LED OCD and the LED emitter.
One way to describe the results, trying to keep it simple.
LED OCD with regular bulbs - 9/10 (not perfect, but very good)
LED OCD with non-ghosting, tweaked - 8/10
LED OCD with non-ghosting, defaults - 7/10
No LED OCD, non-ghosting - 5/10 (depends heavily on the manufacturer and era)
No LED OCD, regular bulbs - 3/10 (depends heavily on the manufacturer and era)

Quoted from herg:

Yes, it will still fade up and down. Since non-ghosting bulbs sometimes turn on, sometimes don't at those low brightness levels (20% or so), you can get flicker if that is included in the profile. This does come into play during LED OCD fades as well as when the game is doing the fade effects.
To avoid the flicker you have to tell the LED OCD to avoid everything 1%-39% or something like that, depending on the bulbs. As a result, when LED OCD is doing fades, it has to go directly from 0% to 40%, so the fade is not as smooth as you can get with standard bulbs.