Roller Coaster Tycoon.
It just begs to be redone with that unique layout, but horrible code and lackluster theme. I'd lose everything but the layout and make it a Tron 1982 theme. The roller coasters would turn into light cycle tracks, they are already red, yellow and blue. The drop targets up the middle could be incorporated for the MCP. Scrambled eggs would now be Dumont on his spinning platform. Troll could be turned into Sark. I'd get rid of the DMD and put an LCD in it with movie clips and custom animation. I wish I had the time and ability to do something like this.