I like where you are going with this, now do you dislike the original themes or just going on layout and gameplay?
Heres some of mine:
I like No Fear but I think the theme is terrible. You would need a theme that's fast and non stop to match the gameplay though. I would do Fear and Loathing in las Vegas, but keep all of the art from the original book as much as possible that ralph Steadman did. I would turn the skull into Hunter S. Thompson and use Call outs from the movie though.
Bram strokers Dracula is my least favorite theme in pinball but a fun game. I think that would work for The Big Lebowski. When the coffin pops open it can have the little toe in it. Bats could be Donny mode where you hear all of the great lines that Walter uses on Donny. The castle can be a a bowling alley. The video mode can be where Walter wails on that car. Mist Multiball can be "Spare" multiball where you need to hit a spare.
I have always wanted to retheme an old beat up EM to be all Bettie Page, just use photos and artwork of here and keep the chimes. Now that's classy. I really want to do this someday.