Don't drive on the Ohio turnpike, through construction zones, and UNKNOWINGLY pick several screws with your tires. Get to Pittsburgh when your low tire light comes on. Then go out to check on your car on Friday and see it has a flat tire. Get eliminated early so you can spend ALL DAY Saturday looking for a tire store that's open that has 255/35/19 tires in stock so you can go back home. (One screw was through the sidewall so it couldn't be plugged)
Other than that, I have no pointers.