Does the K in Rock and the U in Guns work OK? These are in the same row as O in the lamp matrix. Could be diode or grounding issue in the row ?
Review the matrix diagram and see if there are other weird symptoms in related lamps. There are threads and videos on debugging lamp and switch matrices.
I'd start there before thinking about programming problems, unless there are posts about this as a known problem. You can check and post in the GNR Club thread - https://pinside.com/pinball/forum/topic/guns-n-roses-gnr-members-only