Since the hole goes all the way through the board I would route out the area, install a new piece of circuit board using a lap joint and then install with epoxy and fill any gaps.

http://www.circuitmedic.com/guides/3-5-2.shtml

You could also just fill the area with epoxy. Circuit Medic has some colorants for epoxy that are pretty cool.

The section with a lap joint will stand up to just about anything. Once you get the hang of it, it only takes a few minutes to create the replacement piece. In your case just do the lap joints on the two sides to avoid the other eyelets.

The JB Weld should work fine. I don't think there's any magic to the other types of epoxy.

A lot of the standards are oriented towards rework (to fix design flaws or manufacturing issues) rather than repair. In a rework situation the board has to look like new when you're done. People get upset when they get their brand new, multi-million dollar MRI machine and the boards look like they've been worked on before.

Thanks for posting pictures. Look forward to seeing the end result.