A friend of my son's in his early 30s came over for the game yesterday and was so intimidated he only watched others for about 45 min before playing a couple games of the Simspons.
I might tell someone the main objective of a game, "you're trying to collect all the jewels to battle the genie".... As they light modes I might say "Ok, you activated Lightning Lamp, now beat the crap out of it til the countdown ends."
Aside from that, let 'er rip.