Most likely. I think there is an LED on the board that should be lit when it is powered. Did you notice if it was when it was working?
Anyway. The other connectors go off to the optos themselves. So if they are all out I would think the board is not getting power or ground. It is a very easy task to remove. Pop off a few connectors and usually 3 or 4 screws holding to the playfield. 5 minutes.
Hopefully you or someone is comfortable with a soldering iron. As long as it is on the bench re-flow the solder on all of the header pins. Easy task and low risk as long as you don't keep the soldering iron on them so long it lifts the traces. You won't be heating any delicate components.
Take a quick read on soldering tips or watch some youtube videos. It is a good skill to have. One trick with the old solder is to ad a little new solder to help the old stuff melt quicker.
But look at the connector also. The wire can come loose. Take a small flat head jewelers screw driver, like you would use for repairing glasses, and make sure they are seated tight.
Edit: I just took a quick look at the schematics online and I do not see and LED on the board to let you know it is working. If I think about it I can try to check mine when I get home.