Quoted from Eryeal:Agreed - autographs are like photographs. They really only hold value to the person that received them. So if like the other poster said - they traveled the country and got multiple autographs for STTNG - that holds major value to them because of those memories. But for someone else? Minimal value because they don't have the connection to the autographs. It's a lot different to say "I traveled around the country to get these!" vs "I bought them from someone who said they traveled across the country to get these! I'm assuming they are legit."
I think it really only works in some cases. For example, trekkies like myself are borderline insane. We buy star trek stuff that other people think is crap. I bought a Leonard Nimoy autograph in an auction for $190. To some people, it's worthless. To me, it is something I value even if I was not the person he autographed it for.
Many Trekkies are unable to travel around the country to get all the autographs but would kill for it. Now, lets say they are after the Pinball Machine. Two options, one with the entire cast and the other without. Assuming the price was reasonable to them. They would most definitely buy the autographed ST:TNG.
That said, the odds are that will never happen as like myself who got the backglass autographed will never sell it anyway. IF the autograph is for something with a cult following like Star Trek or Star Wars or Doctor Who and so on... Autographs = Awesome.