I assume that a quick play at the seller's house to check out correct function of the game doesn't exclude it. Here are the games I bought with no prior experience playing them:

MET
IM
Congo
DH
NF
Jumping Jack
Fathom
X's and O's
Vector
Hot Hand

The ones I didn't like enough, I sold (usually at a small loss). Cost me about as much as a family movie night. Did you ever regret taking your family out to a movie? Same thing.

CrazyLevi's point is that the cost of admission is a lot higher with NIB. Buying NIB is like taking the family to Disney, while buying a $1200 game is like going camping at the beach with a metal detector.

Metallica is the only NIB I've bought without playing. It was a gamble, but I knew it had a lot going for it: best art ever, in-line drops, metal ramps, the FUEL shot, and Sparky.