Oof. Sorry to hear that. I've got a Flintstones on route that just started having trouble. I think that the chips on the mpu all need to be reseated.
So, start simple. Print out the table showing the switch matrix and mark down what is not working. Verify the wiring on that segment. Look for loose or broken leads inside the molex connectors. If you have a switch tester, like the siegecraft one, you can see quickly if it's the board or the wiring, as well.
Given the time line, I'm guessing this is mostly connector issues. Try buffing the headers with some steel wool before reinserting.
And upload a picture of the marked up switch matrix so we can see it and make suggestions.