Hi Kruz,
Although far from an expert, I am a tube audio enthusiast. I started by rebuilding vintage tube radios and progressed to amps. I'm currently running a Scott 299a into a couple of Klipsch KG4 horn speakers. Horns and tubes work very well together by the way. It's a modest setup by tube standards but I love the sound.
By all means give it a try. Since you have sharp ears you'll really appreciate the ability to tailor the system sound by tube rolling (swapping tubes to achieve different sound characteristics). It's well worth trouble and very satisfying.
If your not aware of it already, AudioKarma has a pretty good tube audio section: http://www.audiokarma.org/forums/index.php
Enjoy the journey!
Randy