For stern Sam & White Star systems Flipper Fidelity has a hole/cut-out in the PVC Panels for your USB Stick so no need to remove it.
Not sure what Michaels doing for Spike yet.
On my LED Back Box Kits it's 2 nuts, 4 fender Washers (1 on each side of the PVC Panel for stability) & 2 Wing nuts.
Like Rob said it only takes a few minutes.
If it's an older Stern title, you'll probably never need to remove it to update code.