I use dedicated build plates for each material. I prep the plate for PETG with Windex, and alcohol for the PLA (per the Prusa manual). I get excellent results with both, and haven’t had any issues switching between materials. I do push a little extra through during the change filament procedure just to be sure.
I really like the Prusa filaments, both PETG and PLA. I wish shipping wasn’t so costly. Hatchbox PLA is a little stringy. Amazon Basics PLA is a stringy mess. I could probably dial some of that out with my slicer settings. I just haven’t spent the time and effort.