I do have a small CNC that I used for milling plastics, but I've since given that up for a multitude of reasons and now outsource them to be laser cut (FYI, the lasers that come with the CNC machines are not powerful enough to do much besides some shallow etching or cutting of soft thin woods or thin colored acrylics). As others have stated, you cannot cut clear materials with these low wattage diode lasers.
To have the versatility to cut clear materials, thicker materials, and harder materials, you need a CO2 laser. Glowforge is nothing but a 40W CO2 laser cutter at an exorbitant price. A OMTech 40W CO2 laster will cost you less than $500 vs. $3500 for the base model of the Glowforge. Sure it doesn't come with a swanky online subscription to make it work or the online repository, but who cares. Also, you need to read in detail about these serious pieces of machinery. The commercials have one sitting in the middle of a nice office, but what they don't tell is they require active ventilation to the outside and water cooling, so don't expect to just set one up in your home office or even shop without venting it to the outdoors. If I had room in my garage and a way to vent it I would certainly own one, but unfortunately I just don't have the proper space to put it in.
Also, don't get me started about how they call the Glowforge a "laser printer" (it is a CNC laser cutter/engraver). Words mean things, and this machine is anything but a laser printer. With a laser printer a laser is used to apply a negative charge to a photoconductive drum or belt which toner adheres to. The toner is then transferred to paper or other medium, and is cured via a combination of heat and pressure. Also, I won't bore you with details about PDL languages (e.g. PDL, PostScript, etc.) that laser printers utilize verses the g-code language of various types of CNC machines. Heck, I could use the same logic as Glowforge and call the laser sight on my Glock is a laser printer (I point a laser at something, pull the trigger, and it prints a nice hole in whatever I'm aiming at).