The main thing is you can't skimp on memory. 4GB of memory was considered inadequate 5 years ago. 8GB is the current standard today, and 16GB will probably be the new standard in 5 years. Trust me, Windows 10 and Chrome love hogging memory (without heavy tweaks and optimizations). If you go with just 4 you'll quickly see performance go downhill with a few Chrome tabs open, plus this will further wear out your main OS drive quicker. It will only get worse with time.
As far as drives, most will have an SSD (likely NVMe). Not an issue there.
